This included Sanger sequencing of the entire coding sequences of SPINK5 and ADAM metallopeptidase domain 17 (ADAM17), as well as 8 genes known to cause autosomal recessive congenital ichthyosis (NIPAL4, CYP4F22, ALOXE3, ALOXE12B, TGM1, PNPLA1, ABCA12, CERS3, FATP4, and ABHD5) and pustular psoriasis (CARD14 and IL36RN). Here, ABCA12 is linked to autosomal recessive congenital ichthyosis.