A prostate cancer related module was investigated (due to its significant enrichment on KEGG prostate cancer pathway), which has DEGs as PDGFRB, PDGFB, SNX2, EGFR and DECGs as (PDGFRA, PDGFRB), (SNX4, PDGFRB), (PDGFB, PDGFRA), (SNX2, PDGFRA), (PDGFRB, PIK3R2), (EGFR, PIK3R2), (EGFR, AREG). This evidence concerns the gene AREG and Familial prostate cancer.