ADIPOQ and breast cancer: In the subgroup of negative family history of breast cancer, the AUC was 0.523 and the cutoff value of 1.42 μg/ml of HMW adiponectin (J: 0.048) significantly discriminated the cases from controls after adjusting for menopausal status (P = 0.007, OR = 0.779, 95%CI, 0.650–0.935) (Table 5).