We recently discovered that UC-112, [5-((benzyloxy)methyl)-7-(pyrrolidin-1-ylmethyl)quinolin-8-ol], is a potent, selective survivin inhibitor (Fig 1).[19] UC-112 inhibits tumor cell growth in several cancer cell lines in vitro and suppresses melanoma tumor growth in vivo. The gene discussed is BIRC5; the disease is cancer.