HMGB1 and Miyoshi myopathy: These data demonstrate that at concentrations ranging from 0.1 μM to 1 mM, which are the concentrations obtained in human serum, following ingestion of therapeutic levels of aspirin, salicylates effectively suppress the chemoattractant activities of HMGB1 in HMGB1-secreting MM cells and suppress the MM malignant phenotype induced by HMGB1.