TACC3 and neoplasm: After filtering, the only chimeric transcript identified was the predicted driver FGFR3–TACC3 fusion, previously described in IDH wild-type gliomas11, 12, 13, which was seen in two of the IDHwt-non-1p/19q co-deleted tumours—patients 2463 and 2441; Of note was that patient 2463 carried an IDH2 intron-5 mutation (c.679-28C>T).