CD40 and myeloid sarcoma: A subset comparison of patients and unaffected controls homozygous for the rs1883832 C allele (CC) also demonstrated a significant decrease in CD40 expression on the total B—lymphocytes of MS patients compared to controls (Fig 3B; p <0.0001) The relative proportions of total B-lymphocytes and subsets as a percentage of total white cells were not affected by genotype or phenotype (data not shown).