However, although in vitro evidence suggests a pro-tumorigenic role for p120 phosphorylation, the role of p120 phosphorylation in tumor progression is largely unknown and only a couple of studies have correlated p120 Y228 phosphorylation with progression of oral squamous cancer [38] and aggressiveness of glioblastoma [39]. The gene discussed is CTNND1; the disease is glioblastoma.