ANXA7 and glioblastoma: For example, the cancer genome atlas research network suggested that the ANXA7 might act as a tumor suppresser gene in glioblastoma, and another study found that haploinsufficiency of the tumor suppressor ANXA7 due to monosomy of chromosome 10 promotes glioblastoma cell tumorigenicity by augmenting EGFR signaling16, 26.