While IL-10-/- mice monoassociated with E. faecalis OG1RF had severe inflammation in the distal colon (OG1RF histopathological score: 7.2±1.2), colitis was partially impaired in E. faecalis ΔepaB (ΔepaB score: 4.7±2.3; *p<0.05) and was almost completely abrogated in E. faecalis Δlgt monoassociated IL-10-/- mice (Δlgt score: 2.3±2.3; ****p<0.0001) (Fig 1B and 1C). The gene discussed is IL10; the disease is colitis.