VEGFA and ischemia: For example, LLLT can positively affect hASCs by increasing cellular viability, proliferation and migration [9, 10]; LLLI also enhances vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF) secretion [8]; and Low-level light therapy (LLLT) enhanced tissue healing by stimulating angiogenesis in various animal models of ischemia [11].