The analysis of the genotype frequencies revealed the association of hypertension with the CC genotype and C allele for IL-10 -592C/A polymorphism (p = 0.013, OR 9.400, and CI 95% 1.509–58.568 and p = 0.009, OR 3.830, and CI 95% 1.206–12.546, resp). This evidence concerns the gene IL10 and Hypertension.