For example, the PRKCA gene with the top connecting score of 8 (Figure 3) interacts with 6 genes (INSR, EGFR, RARA, SRC, RAF1, TP53) from MAOCs, where these 6 genes have been reported to be oral cancer related genes according to GeneCards (see Table 2). This evidence concerns the gene EGFR and lip and oral cavity carcinoma.