Several zebrafish models associated with myeloid malignancies have been previously reported, including transgenic zebrafish that exhibit K-RASG12D, NUP98-HOXA9, Stat5 (H298R), Stat5 (N714F), NPM1, tel-jak2a, AML1-ETO, FLt3-ITD, FLT3-TKD (D835Y), MYCN, or MOZ/TIF2 expression. Here, NPM1 is linked to myeloid neoplasm.