At baseline all RA patients had active disease as indicated by a mean (±SD) DAS-28 of 5.76 (±1.35) with no differences in DAS-28 values between patients that subsequently did (3.3 ± 1.55) or did not (3.46 ± 1.73) develop anti-INF or anti-ADA Ab (P = 0.727). Here, CBLIF is linked to rheumatoid arthritis.