NFKB1 and hydrops fetalis: The standardized S. indicus extract (10 μg/ml) contains approximately 0.6 μg/ml or 3 μM of 7-HF, and since we observed similar effects of S. indicus extract at 10 μg/ml and 7-HF at 3 μM (data not shown), we postulated that the effects on the expression of cell adhesion molecules and NF-κB activation seen with the crude extract of S. indicus extract may be related to its content of 7-HF.