Treatment allocation (HR = 1.999, 95 % CI = 1.341–2.980, P = 0.001), albumin level (HR = 1.723, 95 % CI = 1.167–2.543, P = 0.006), tumor size (HR = 1.877, 95 % CI = 1.255–2.806, P = 0.002), and tumor number (HR = 1.359, 95 % CI = 1.114–1.658, P = 0.002) were independent prognostic factors for RFS (Table 2). The gene discussed is ALB; the disease is neoplasm.