We performed immunohistochemistry for p53 and cytokeratin 7 in 44 cases of colon biopsies with IBD-IND and investigated the value of these two markers in predicting neoplastic progression in IBD-IND because our previous study showed overexpression of p53 and cytokeratin 7 in IBD-associated neoplasia in a partially overlapping and partially complementary fashion [17]. Here, KRT7 is linked to neoplasm.