In contrast, weak nuclear staining of p53 and cytokeratin 7 expression were not associated with neoplasia progression (HR = 1.02; 95% CI: 0.99–1.04; P = 0.19 for p53; HR = 0.99; 95% CI: 0.97–1.01; P = 0.39 for cytokeratin 7) (Table 2). This evidence concerns the gene TP53 and neoplasm.