Recently, several studies have shown that anti-37LRP/67LR specific antibodies significantly reduce the invasive potential of HT1080 fibrosarcoma, lung, cervical, colon, prostate, breast and oesophageal cancer cells [30, 43, 47], thus indicating that 67LR plays a critical role in tumor invasion and metastasis through its interaction with LM. Here, RPSA is linked to carcinoma of esophagus.