As a result, four out of top 10 predicted colorectal cancer-related lncRNAs (CRNDE, H19, PVT1, and CASC2) have been confirmed to be associated with colorectal cancer based on recent experimental literatures101, 102, 103 (http://cpfd.cnki.com.cn/Article/CPFDTOTAL-KAXH201309001039.htm). This evidence concerns the gene CASC2 and colorectal cancer.