Pathway analysis of genes induced in common by cytokines and viral infection (Figure 1—figure supplement 2 and Figure 1—figure supplement 3; for clarity only the top 30 correlations are shown) indicated presence of large groups of genes involved in interferon signaling (top correlation for both cytokine data sets compared to the virus data set), activation of IRFs (family of interferon regulatory transcription factors), PRRs, T1D signaling, role of PKR in IFN induction, Jak/Stat signaling (activated downstream of IFNs and STATs), and so on. Here, EIF2AK2 is linked to type 1 diabetes mellitus.