Besides, since pimozide is a well-known antagonist of serotonin 5-hydroxytryptamine receptor 7 (5HT7), which was overexpressed in human hepatocellular cancer (Data not shown, [49]), whether 5HT7 expression is associated with STAT3 activation in HCC cells is required to investigated in future. Here, STAT3 is linked to hepatocellular carcinoma.