In addition to treatment regimes, other currently identified potential risk factors for hypoglycaemia in type 2 diabetes include exercise [17], increased age [18], presence of co–morbidities [18], hypoglycaemia unawareness [18], dietary mistakes [19], excessive dieting [20] or weight loss, alcohol [21], number of years since diabetes diagnosis [22], and time since insulin initiated [23],. This evidence concerns the gene INS and type 2 diabetes mellitus.