Whether similar cellular changes are employed by the RANKL/RANK signaling axis during salivary gland tumorigenesis—as observed in tumor cells of the mammary gland [18, 21, 25, 42, 50, 52] as well as of the prostate gland [12, 20, 53], kidney [11], and liver [51]—is a research question to be addressed by future studies. This evidence concerns the gene TNFRSF11A and neoplasm.