In the current analysis, higher IL‐10 or IFN‐γ was only associated with asthma in the context of high IL‐5 and IL‐13 productions; children who produced IL‐10 but no IL‐5 (Class 1), or IFN‐γ but no IL‐5 (Class 2) were not at increased risk of asthma. Here, IL5 is linked to asthma.