Children in Class 3 (moderate IL‐13 production in response to HDM allergen) were at a modest risk of mite sensitization compared to Class 0 (OR 2.93, 95% CI 2.24–3.81, P < 0.001), but did not differ significantly from Class 0 in relation to wheeze or asthma (P = 0.53 and 0.38, respectively). This evidence concerns the gene IL13 and asthma.