Since LASP1 has been shown to have a functional role in cell viability, motility and tumor dissemination [13, 32–34], we also investigated cell migration, adhesion and proliferation in melanoma cells before and after LASP1 silencing by using a modified Boyden chamber assay, a fibronectin adhesion assay and an MTT viability test, respectively. This evidence concerns the gene LASP1 and neoplasm.