Among the 8 enrolled studies, 4 were retrospective cohorts,17–20 3 were cross-sectional,12,13,21 and 1 was case–control study.14 Two studies were multi-center studies.13,18 A total of 1297 AIH patients, among whom 195 were anti-SLA seropositive, were involved. The gene discussed is SLA; the disease is autoimmune hepatitis.