In S. aureus isolate P skin infected mice, IgG levels against alpha toxin, Efb, EsxA, EsxB, IsaA, IsdA, IsdH, lipase, LukD, LukE, LytM, Nuc, PG, PrsA, and SA0104 were significantly higher than in mice with placebo skin infection. The gene discussed is GLRX5; the disease is skin infection.