Comparison of older DMD patients with their age-matched controls (G2 versus G4) using the same parameters resulted in only nine altered proteins: five proteins more abundant in DMD (CK-M, adiponectin, fructose-bisphosphate aldolase A, L-lactate dehydrogenase B chain and haemoglobin β) and four in healthy subjects (gelsolin, phosphatidylcholine-sterol acyltransferase, cadherin-13 and cartilage acidic protein 1) (Table 3). This evidence concerns the gene ADIPOQ and Duchenne muscular dystrophy.