The top 10 proteins with the lowest P-value were more abundant in DMD patients and either involved in muscle energy metabolism (pyruvate kinase PKM, L-lactate dehydrogenase B chain, CK-M, alanine aminotransferase 1, β-enolase, carbonic anhydrase 3, fructose-bisphosphate aldolase A), in sarcomere organization (myomesin-3, myosin-7) or costamere organization (vinculin). The gene discussed is CA3; the disease is Duchenne muscular dystrophy.