Hypoxia induced the binding of HIF-1α (Figure 3B), but not HIF-1β (Figure 3C), to the CTGF promoter in NTC cells, but not in TAZ knockdown cells, demonstrating that TAZ recruits HIF-1α to the CTGF proximal promoter in hypoxic breast cancer cells. The gene discussed is WWTR1; the disease is breast carcinoma.