FGF23 and hyperplastic polyp: In this study, we performed genome-wide linkage and whole-exome sequencing analyses on an MP pedigree and identified a novel (not reported in dbSNP 138, 1000 Genome Project, or NHLBI GO Exome Sequencing Project) heterozygous mutation in FGF23 (c.35C>A; p.A12D) that was strongly associated with MP.