To investigate the effect of TGF-β secretion on HCC cell migration and invasion, Bel-7402-EV and/or Bel-7402-MUC1 cells were treated with or without different doses of exogenous TGF-β1, TGF-β1 siRNAs or TβRI inhibitor (SB431542). Here, TGFBR1 is linked to hepatocellular carcinoma.