A study by Loveday et al. reported that germline mutations in the RAD51D gene (MIM:602954) confer susceptibility to OC in 0.9% of HBOC families (predominantly with more than one case of OC) and estimated the relative risk (RR) at 6.3 for OC and 1.32 for BC [14]. This evidence concerns the gene RAD51D and breast cancer.