WT1 and chronic myelogenous leukemia, BCR-ABL1 positive: WT-1 represents a TAA as it is overexpressed in both leukemias (AML, CML, myelodysplastic syndrome [MDS], and ALL) and various solid tumors (ovary, breast, renal cell, colon, lung), where it acts as a putative oncogene[175–179].