Since this strategy is a platform, it is very likely that by exchanging the mAb on the surface, for example, against B cell malignancies (anti-CD19 or CD20) it will be possible to target many types of B-cells malignancies such as mantle cell lymphoma (MCL), and chronic lymphocytic leukemia (CLL) in a specific and efficient manner. The gene discussed is CD19; the disease is B-cell chronic lymphocytic leukemia.