HLA-G and Hepatomegaly: In contrast, adulthood (age at diagnosis > 15 years; p = .04) (Figure 3C), presence of lymphadenopathies (p = .03) and hepatomegaly (p = .03) (Figure 3D and 3E), skin lesions (p = .04) (Figure 3F), increased serum LDH (≥ 450U/l; p = .001) (Figure 3H) and β2-microglobulin (≥ 3 mg/l; p = .02) were all associated with a poorer outcome (Table 4).