To study the localization of both 18K and HMW FGF2 in glioblastoma cells, T98G cell line derived from human glioblastoma was transfected with HA-tagged constructs expressing HMW-FGF2 (HA-HMW) or 18K-FGF2 (HA-18K). This evidence concerns the gene FGF2 and glioblastoma.