In humans, asymptomatic noninflammatory AAA selected for surgical repair due to size criteria lack significantly increased 18 F-FDG uptake on PET while at the same time, focal 18 F-FDG uptake is identified on autoradiography co-localizing to focal accumulations of CD45-, CD3-, and CD20-positive leukocytes on IHC with very little contribution of macrophages [24]. The gene discussed is PTPRC; the disease is triple-A syndrome.