Most recent studies from clinical findings show that when WWOX gene undergoes homozygous mutations at specific bases, patients are WWOX-deficient  in the body, resulting in  growth retardation, small brains, ataxia, epilepsy, mental retardation, and early death (Biochim Biophys Acta 1846: 188, 2014; Oncotarget 5: 11792, 2014; review articles). This evidence concerns the gene WWOX and Ataxia.