We recently demonstrated that five urinary biomarkers measured on post-operative days 1–3: NGAL (urinary), interleukin-18 (IL-18), kidney injury molecule-1 (KIM-1), liver fatty acid binding protein (L-FABP), and albumin were independent predictors of long term survival in patients with clinical AKI.[6] However, based on the results we present in this paper we can conclude that the value of pNGAL as an independent marker of long-term survival is weak. This evidence concerns the gene IL18 and acute kidney injury.