SERPINA1 and neoplasm: Among other altered genes, these included greater expression in GEP-A (vs. GEP-B) PDAC of the CEACAM6 gene, as well as of genes associated with the inflammatory response and chronic pancreatic diseases such as the integrin β4 and β6 genes (ITGB4 and ITGB6), the cytochrome b-245 beta polypeptide (CYBB), lysozyme (LZY), the SERPINA1 antiproteinase and the antitrypsin serpin peptidase inhibitor genes, together with genes involved in tumor metastasis and invasion –e.g.