The miR-148a miRNA possibly mediates overexpression of genes involved in tumor cell growth (e.g. acetyl-CoA sintetase, ACSL5), migration (e.g. the TSPAN15 tetraspanin) with an effect also on both apoptosis and immune responses (e.g. the TNFRSF21 tumor necrosis factor receptor); in turn miR-23a inhibits the antioxidative effect of the coenzyme Q10 homologe A (COQ10A) gene. This evidence concerns the gene ACSL5 and neoplasm.