Histological analysis (hematoxylin and eosin staining, HE) revealed that all tumors formed by SK-N-SH cells, independently of ATM expression levels, were composed of sheets and nests of large cells, with large nuclei and prominent nucleoli, and scant to moderate amounts of cytoplasm, thus resembling undifferentiated large cell neuroblastoma [21] (Figure 7C right column). Here, ATM is linked to neuroblastoma.