AKT1 and neoplasm: In addition, when injected subcutaneously into athymic CD1 mice (5 × 106 cells per mouse), mutant AKT1-E17K was able to promote tumour formation in 9 out of 13 mice with a latency of 4–10 weeks as illustrated in the Kaplan-Meier curve of Figure 3C while BEAS-C and BEAS-AKT1-WT cells were unable to grow in vivo (n = 13).