To understand the molecular basis of TUSC2-erlotinib cooperativity and identify specific pathways involved, we used high-throughput qRT-PCR arrays enabling multi-parallel expression profile analysis of 86 receptor and non-receptor tyrosine kinase genes across TUSC2-deficient wild type EGFR A549, H1299, and H322 NSCLC lines. Here, NTRK1 is linked to non-small cell lung carcinoma.