IFNA1 and infection: An analog of 5′pppRNA, derived from the 5′ and 3′ untranslated regions of VSV genome (Schlee et al., 2009), has been shown to induce IFN expression and multiple innate antiviral responses, including IRF3/7, to control infections with IFV-A, DENV, VSV, HCV, and VACV (Goulet et al., 2013; Olagnier et al., 2014).