The frequency of ESAT-6- and CFP-10-specific IFN-γ secreting cells was higher in HIV-uninfected TB patients than HIV-uninfected controls (median ESAT-6108 [IQR 18–256] vs. 4 [IQR 0–15] SFU, p = 0.01; median CFP-10 74 [IQR 32–247] vs. 9 [IQR 0–35] SFU, p = 0.001; Figure 2B and 2C). Here, IFNG is linked to tuberculosis.