BTG1 and metastatic malignant neoplasm in the lymph nodes: Multivariate analysis using Cox's proportional hazard model showed that venous invasion, distant metastasis and TNM staging (p < 0.05), but not age, sex, depth of invasion, lymphatic invasion, lymph node metastasis, Lauren's classification or BTG1 expression (p > 0.05) were independent prognostic factors for overall gastric cancer patients (Table 3).