MHC class I negative tumor cells are converted to MHC class I positive tumor cells with the assistance of Interferon gamma (IFNγ) at a rate \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$c_{3}\frac {\text {IFN}{\gamma }}{k_{1} +\text {IFN}{\gamma }}C_{MHCI^{-}}$\end{document}c3IFNγk1+IFNγCMHCI−. This evidence concerns the gene IFNG and neoplasm.