CD8A and neoplasm: We assume that effector CD8 + T cells can proliferate locally upon recognition of the corresponding tumor antigen presented by MHCI positive tumor cells at a saturable rate equal to \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$k_{p3}\frac {C_{MHCI^{+}}}{\epsilon +C(t)}T_{E3}\phantom {\dot {i}\!}$\end{document}kp3CMHCI+ε+C(t)TE3.