CCR6 and neoplasm: It was further found that the supplementation of Ccr6−/− mice with TAMs restored the efficiency of tumor growth (measured by weight of tumor-bearing mammary glands) within these mice to that seen in the Ccr6WT, whilst Ccr6−/− mice that received sham injections displayed reduced tumorigenesis (Fig. 6d) as seen in the spontaneous model (see Fig. 1).