IL1B and chronic rhinosinusitis without nasal polyps: They could also suppress the protein production of IL-1β (Fig. 5b) and tumor necrosis factor (TNF)-α (Fig. 5d) from sinonasal mucosa from CRSsNP and eosinophilic CRSwNP patients, but not from non-eosinophilic CRSwNP patients.